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British Medical Journal 2018 UK Research Paper Finalist

last modified Aug 02, 2018 03:54 PM

Charlotte ColesDr Charlotte Coles, Reader in Breast Radiation Oncology and Chief Investigator of the IMPORT LOW trial was nominated with the rest of her research team for UK British Medical Journal Research Paper 2018 award.

IMPORT LOW is the first phase III trial reporting 5-year outcome data for local relapse and adverse effects after partial breast radiotherapy delivered using standard external beam radiotherapy techniques. It is unique by including very comprehensive patient-reported outcome measures. At 5 years, partial breast radiotherapy delivered using a simple and standard technique, showed no increase in local relapse rates compared with whole breast radiotherapy, and produced equivalent or reduced late adverse effects. This technique is implementable worldwide, requiring  existing equipment and no/minimal additional resources.

Partial breast radiotherapy is now recommended as standard of care for selected patients by the UK Royal College of Radiologists Breast Radiotherapy Consensus, is included in the draft National Institute of Clinical Excellence breast cancer guidance, has been developed as an impact case by the National Institute of Health Research and is already changing practice internationally.

IMPORT LOW is funded by Cancer Research UK and the trial is sponsored by the Institute of Cancer Research.

Charlotte attended the awards ceremony with two of her co-authors, Jo Haviland (Senior Statistician representing the Institute of Cancer Research Clinical Trials and Statistics Unit) and Prof John Yarnold (Institute of Cancer Research and former Chief Investigator) on 10 May 2018.

 Coles 2018 BMJ Awards